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Linda Crane Mitchell Archana V. Hegde 《Journal of Early Childhood Teacher Education》2013,34(4):353-366
This study examined the beliefs of in-service teachers working in inclusive classrooms regarding developmentally appropriate practices and how those beliefs affected their attitudes toward, knowledge of, and comfort levels regarding working with children with disabilities. A mixed-method approach was utilized and data were collected through the use of three survey instruments: Teacher Belief Scale and Instructional Activities Scale (Hart et al., 1990) and the In-service Teacher Self-Report Survey (Mitchell, 2002). Data were also collected through open-ended questions to assess Teachers' perceived level of preparation for the inclusive classroom. This study also examined whether education or experience levels had an influence on Teachers' perceptions regarding inclusive practices. Results of the study indicate that there is not a significant relationship between in-service Teachers' beliefs regarding developmentally appropriate practices and their attitudes toward, knowledge of, and comfort levels regarding inclusion. Additionally, results indicate that the Teachers' levels of education or experience do not necessarily indicate that they are prepared to meet the needs of the inclusive classroom environment. Implications regarding the preparation of and ongoing training needs of teachers are discussed. 相似文献
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Archana Verma Rakesh Kapoor Rama Devi Mittal 《Indian journal of clinical biochemistry : IJCB》2017,32(3):292-300
Adhesion molecules play a key role in cancer progression and tumorigenesis. Genetic polymorphism of adhesion molecules may alter the normal functioning thereby leading to bladder cancer susceptibility. Hence we aimed to evaluate three SNPs of CD166 gene (CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G) in bladder cancer patients and normal controls of North Indian population. A total of 270 healthy controls and 240 confirmed bladder cancer patients were recruited for this study. Three SNPs of CD166 gene viz. CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G were selected for this study. CD166rs6437585 C/T and CD166rs10511244 C/T were genotyped by Taqman allelic discrimination assay and CD166rs1157 A/G was genotyped by PCR–RFLP. The statistical analysis was done using the SPSS software, version 16.0 (SPSS, Chicago, IL), and p < 0.05 was considered statistically significant. Haplotypic analysis was done by using SNP analyzer version 1.2A. CD166rs6437585 C/T and CD166rs10511244 C/T showed significant association with reduced risk in bladder cancer while CD166rs1157 A/G showed significant high risk along with association at genotypic and allelic levels. Haplotypic analysis showed 1.8-folds risk in CCG combination, whereas CTA and TCG showed significant association with reduced risk. Further stratification on the basis of smoking, tumor grade/stage and BGC therapy revealed no association of these three polymorphic sites of CD166. Our study suggests that CD166rs6437585 C/T and CD166rs10511244 C/T are predictive for the reduced risk of bladder cancer, whereas CD166rs1157 A/G had shown significant association with high risk of bladder cancer in North Indians. This somehow suggests that CD166rs1157 A/G can be used as a marker for risk prediction of bladder cancer. 相似文献
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The Enterprise mobility communication technology provides easy and quick accessibility to data and information integrated into one single touch point device. This device incorporates or integrates all the processes into small applications or App and thus increases the workforce capability of knowledge workers. “App” which is a small set of programming statements installed on a mobile device. It facilitates the easy retrieval of information while the users are mobile. A single touch point can be loaded with the required data and information all the time. The readiness and availability of data facility can reduce the turnaround response time. The application of mobile technology has already picked up the market in distinguished domain worldwide. In the Indian education sector this technology is yet to be adopted. This paper aims at showing how enterprise mobility can facilitate the University system and user preferences in the mobile App. The paper also highlights how data mining techniques can be applied to various processes, hence exploring user patterns. A new model using data mining techniques is proposed. 相似文献
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Output reversibility involves dynamical systems where for every initial condition and the corresponding output there exists another initial condition such that the output generated by this initial condition is a time-reversed image of the original output with the time running forward. Through a series of necessary and sufficient conditions, we characterize output reversibility in linear discrete-time dynamical systems in terms of the geometric symmetry of its eigenvalue set with respect to the unit circle in the complex plane. Furthermore, we establish that output reversibility of a linear continuous-time system implies output reversibility of its discretization. In addition, we present a control framework that allows to alter the system dynamics in such a way that a discrete-time system, otherwise not output reversible, can be made output reversible. Finally, we present numerical examples involving a discretization of a Hamiltonian system that exhibits output reversibility and an example of a controlled system that is rendered output reversible. 相似文献
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Singh B Goswami B Gupta N Bajaj AD Mallika V 《Indian journal of clinical biochemistry : IJCB》2011,26(1):41-45
Preterm delivery is a major contributor for neonatal mortality. Intensive research is underway to establish a reliable biomarker
that can ascertain the risk of preterm delivery in pregnant women. The aim of our study was to evaluate the role of various
biochemical parameters as potential biomarker for risk assessment for preterm labor. Forty women presenting with preterm labor
and 40 women who delivered at term were included in the study. Parameters that were evaluated include corticotrophin (ACTH),
prolactin, thyroid stimulating hormone (TSH), ferritin and Alkaline Phosphatase (ALP). Serum ACTH, ferritin, ALP and Ferritin/Iron
ratio were significantly higher in the subjects who delivered prematurely as compared to the controls. Comparison of sensitivity,
specificity, likelihood ratio, positive and negative predictive values for different cut offs for ACTH, ferritin, ALP and
ferritin/iron ratio was carried out. Ferritin emerged as the best marker with area under curve of 0.96 as compared to 0.88
for ACTH, 0.825 for ALP and 0.735 for ferritin/iron ratio. Our study establishes the superiority of ferritin as a predictive
biomarker for preterm labor as compared to the rest of the parameters evaluated. 相似文献
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Sweta T. Kothari Ranjana A. Deshmukh 《Indian journal of clinical biochemistry : IJCB》2006,21(1):15-26
Cytokines, viral load and opportunistic infections play an important role in HIV-disease progression. Hundred children vertically
infected with HIV were enrolled to determine mRNA levels of TNF-α, IL-10, IL-4 and IFN-γ. These levels were estimated by amplifying
cytokine mRNA from peripheral blood mononuclear cells. Severity of HIV was staged by the reduction in CD4
+ T cells and the onset of opportunistic infections. IL-10 mRNA levels were observed to increase with the severity. Despite
the rising IL-10 mRNA levels, TNF-α mRNA levels increased with severity of HIV and decrease in CD4
+ T cell counts. IL-4 mRNA levels increased with the reduction in CD4
+ T cell numbers. Depleting mRNA levels of IFN-γ contributed to the worsening of HIV disease. Increase in TNF-α and IL-4 levels
appended to the disease severity by upregulation of the viral replication. Increased IL-10 levels and decreased IFN-γ levels
predisposed the children to HIV associated opportunistic infections, which in return contributed to cytokine disarray. 相似文献
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Archana Singh 《Education and Information Technologies》2017,22(4):1515-1526
The youth power to speak their mind, recommendations and opinions about various issues on social media cannot be ignored. There is a generated by students on social media websites like, facebook, Orkut, twitter etc. This paper focusses on the extraction of knowledge from the data floated by the University students on social websites in different categories. The paper proposed a framework to mine the social media raw data using data mining techniques. The data mining techniques K-means are used to mine the data to extract useful information in education sector. The analytical model can help the educational institutions to develop strategies. The knowledge outcome of this paper is to identify the frequent types of flow and exchange of data by University students. This knowledge can be enhanced by knowing students’ behavior and interests on the social network. 相似文献
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Ramesh Chandra Manisha Tiwari Ritu Aneja Sujata K. Dass Archana Sharma 《Indian journal of clinical biochemistry : IJCB》2000,15(2):148-154
We investigated the effect of cholesterol and the metalloporphyrins cobalt mesoporphyrin (CoMP) and chromium protoporphyrin
(CrPP) on phospholipase A2 (PLA2) activity and the consequent hepatic mitochondrial stability as well as on lipid concentrations. Our studies revealed that
on administration of cholesterol, CrPP, CoMP as well as simultaneous adminstration of cholesterol and CrPP, there was an inhibition
of PLA2 activity. These moieties may therefore, be agents for preventing destabilisation of the mitochondrial membrane and the consequent
pathological conditions which may arise due to membrane lysis. Our results revealed that cholesterol administration increased
phospholipid concentration, albeit by modest amounts. Although the independent administration of metalloporphyrins led only
to minor elevations in phospholipid concentration, the simultaneous administration of cholesterol and CrPP generated a steep
elevation in the concentration of total phospholipid. Since cholesterol inhibits PLA2 activity it has the potential of being therapeutic agent for preventing the pathological conditions which may arise due to
membrane lysis. 相似文献